The automation of technical systems all the way to autonomy is one of the current megatrends in industry. Artificial Intelligence (AI) enables the realization of that autonomy. These systems are often part of a larger ecosystem where the failure of such an autonomous system can cause economic or even personal damage. This requires special measures to ensure the functional safety of systems with AI components. Existing methods prescribed by standards such as IEC 61508 are only partly applicable in this context, or do not cover the full scope of the issue of functional safety of autonomous systems. As one of the globally leading research departments on the topic of Functional Safety, we are collaborating with our industry partners in national and international projects as well as bilaterally to solve these problems.